検索結果

Search Results for " renal inflammation "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T10696	CB2 modulator 1		Cannabinoid Receptor
	CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.		Cannabinoid Receptor
T4583	PFI-2 hydrochloride	(R)-PFI-2 hydrochloride,PFI-2 HCl	Histone Methyltransferase
	PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.		Histone Methyltransferase
T1987	PFI-2	PFI2,PFI 2,(R)-PFI-2	Histone Methyltransferase
	PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.		Histone Methyltransferase
T21610	Bradykinin (acetate)		Bradykinin Receptor
	Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzy...		Bradykinin Receptor
T79516	BT424		Src
	BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].		Src
T38384	Nexinhib20
	Nexinhib20 is an inhibitor of the protein-protein interaction between the small GTPase Rab27a and its effector JFC1 (IC50 = 2.6 μM).[1] It inhibits myeloperoxidase (MPO) secretion induced by granulocyte macrophage colony...
T61949	Evogliptin
	Evogliptin (DA-1229) is a DPP4 inhibitor with oral activity. Evogliptin has significant and lasting hypoglycemic effect in mouse model. Evogliptin inhibits the production of the fibrosis and inflammatory in hepatocytes s...

Compounds

CB2 modulator 1

T10696

Synonym:

Target: Cannabinoid Receptor

PFI-2 hydrochloride

T4583

Synonym: (R)-PFI-2 hydrochloride,PFI-2 HCl

Target: Histone Methyltransferase

PFI-2

T1987

Synonym: PFI2,PFI 2,(R)-PFI-2

Target: Histone Methyltransferase

Bradykinin (acetate)

T21610

Synonym:

Target: Bradykinin Receptor

カタログ番号	製品名	別名	ターゲット
T3033	Deoxycorticosterone acetate	DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate	Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor
	Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
TQ0119	Cirsimaritin		GABA Receptor
			GABA Receptor
T3005	4-Hydroxychalcone	P-Cinnamoylphenol	Others , NF-κB
	4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.		Others , NF-κB
T4904	1-Methylguanidine hydrochloride		Others , Endogenous Metabolite
	Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit...		Others , Endogenous Metabolite

天然物製品

Deoxycorticosterone acetate

T3033

Synonym: DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate

Target: Glucocorticoid Receptor, Endogenous Metabolite, Adrenergic Receptor

Cirsimaritin

TQ0119

Synonym:

Target: GABA Receptor

4-Hydroxychalcone

T3005

Synonym: P-Cinnamoylphenol

Target: Others, NF-κB

1-Methylguanidine hydrochloride

T4904

Synonym:

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPK-00138	CXCL16 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall c...
TMPK-00469	CXCL16 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CXC chemokine ligand 16 (CXCL16) is a CXC soluble chemokine, an adhesion molecule and a cell surface scavenger receptor. CXCL16 regulates inflammation, tissue injury and fibrosis. Parenchymal renal cells, vascular wall c...
TMPJ-00379	AOC3 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycop...
TMPJ-00082	NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPJ-00299	LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Lysosome membrane protein II (LIMPII)，also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far e...
TMPJ-00298	CD36 Protein, Human, Recombinant (aa 27-432, His)	Human	HEK293 Cells
	Scavenger Receptor Class B Member 2 (SCARB2) is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlie...